Dual Specificity Phosphatase 3 (DUSP3) (AA 1-185) antibody

Catalog No. ABIN5540300

This Mouse Monoclonal antibody specifically detects in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for Dual Specificity Phosphatase 3 (DUSP3) (AA 1-185) antibody (ABIN5540300)

Target: Dual Specificity Phosphatase 3 (DUSP3)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: AT9E6

Product Details

Binding Specificity: AA 1-185

Purification: Protein-A affinity chromatography

Immunogen: Recombinant human DUSP3 (1-185aa) purified from E. coli.

Isotype: IgG2b

Application Details

Application Notes: The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution for Western blot analysis is 1:3000.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. In Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details

Target: Dual Specificity Phosphatase 3 (DUSP3)

Alternative Name: dusp3

Background: DUSP3, also known as Dual specificity protein phosphatase 3, is ictivate their target kises by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kise superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kises, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli.

UniProt: P51452

Pathways: Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades