IL9 Receptor antibody

Catalog No. ABIN5540440

This anti-IL9 Receptor antibody is a Mouse Monoclonal antibody detecting IL9 Receptor in FACS, Func and EIA. Suitable for Human.

Quick Overview for IL9 Receptor antibody (ABIN5540440)

Target: IL9 Receptor (IL9R) (Interleukin 9 Receptor (IL9R))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL9 Receptor antibody is un-conjugated

Application: Flow Cytometry (FACS), Functional Studies (Func), Enzyme Immunoassay (EIA)

Clone: AH9R7

Product Details anti-IL9 Receptor Antibody

Specificity: This antibody recognizes CD129 / IL-9R alpha, a 57 kDa type I transmembrane glycoprotein expressed at low levels by lymphocytes, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons.

Purification: Protein-A affinity chromatography (> 95% pure by SDS-PAGE)

Immunogen: Human CD129-transfected cell line

Isotype: IgG2b

Application Details

Application Notes: Flow cytometry: Use bright fluorochromes or signal multiplying detection. ELISA. Functional application: blocking.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 95 % pure by SDS-PAGE) Buffer System: Phosphate buffered saline (PBS) Preservatives: 15 mM sodium azide, approx. pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for IL9 Receptor

Target: IL9 Receptor (IL9R) (Interleukin 9 Receptor (IL9R))

Alternative Name: cd129,il9r

Background: CD129 serves as the high affinity alpha subunit of IL-9 receptor. It associates with CD132, the common gamma chain shared by receptors of many different cytokines. CD129 is expressed at low levels by T and B cells, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons. Its signaling (through JAK/STAT pathways) results in proliferative and anti-apoptotic response, which is critical e.g. for intrathymic T cell development and survival of various cell types. The gene for CD129 is located at the pseudoautosomal regions of X and Y chromosomes and it may be related with the development of asthma.

UniProt: Q01113

Pathways: JAK-STAT Signaling, Growth Factor Binding