SRY antibody (AA 1-229)

Catalog No. ABIN5540668

The Rabbit Polyclonal anti-SRY antibody (ABIN5540668) specifically detects SRY in WB. The antibody is reactive with Cow samples.

Quick Overview for SRY antibody (AA 1-229) (ABIN5540668)

Target: SRY (Sex Determining Region Y (SRY))

Reactivity: Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRY antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SRY Antibody

Binding Specificity: AA 1-229

Specificity: This antibody detects SRY.

Purification: Protein A chromatography

Immunogen: Highly pure recombinant human bovine SRY (Met1 - Tyr229) derived derived from E. coli (Cat.-No. AR60006PU-N)

Isotype: IgG

Application Details

Application Notes: Western blot: 1-5 μg/mL.

Restrictions: For Research Use only

Handling

Buffer: PBS

Storage: 4 °C,-20 °C

Storage Comment: Prior to reconstitution store at 2-8°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for SRY

Target: SRY (Sex Determining Region Y (SRY))

Alternative Name: sry,tdf

Background: The "Sex determining region of Y-Gen" (SRY), known as SRY gene, is coding for a transkription factor (TDF for Testis-determining factor). It belongs to the protein family of DNA binding-proteins. The SRY gene is beside other genes used for the determination of the sex in human as well as other mammals. Most mammals have for this purpose a further gene, UBE1. In humans SRY is normally located on the short arm of the Y chromosome. Accordingly, people who possess this chromosome with the corresponding gene, normally have a male phenotype. It does not matter how many copies of the X chromosome are present, even people with a multiple X chromosome (Klinefelter's syndrome) have this. The protein encoded by the gene Testis-determining factor controls the development of male sex.

UniProt: Q03255