ADCY3 antibody (C-Term)

Catalog No. ABIN5540747

This Rabbit Polyclonal antibody specifically detects ADCY3 in WB, IF, ICC and IHC (fro). It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for ADCY3 antibody (C-Term) (ABIN5540747)

Target: ADCY3 (Adenylate Cyclase 3 (ADCY3))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADCY3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-ADCY3 Antibody

Binding Specificity: C-Term

Specificity: Specific for the ~160 kDa Adenylate Cyclase III.

Purification: Affinity Chromatography

Immunogen: Synthetic peptide corresponding to amino acid residues from the C-terminal region of Rat Adenylate Cyclase III conjugated to KLH.

Isotype: IgG

Application Details

Application Notes: Western Blot: 1/2000. Immunohistochemistry. Immunofluorescence: 1/500.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS

Storage: -20 °C

Storage Comment: Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for ADCY3

Target: ADCY3 (Adenylate Cyclase 3 (ADCY3))

Alternative Name: adenylate cyclase type 3

Background: Adenylate cyclase is the enzyme which produces the "second messenger" signaling molecule, cAMP from ATP. Type III adenylate cyclase is localized to the membranes surrounding neuronal cilia. Much is currently unknown about the function of primary cilia in vertebrates, however, recent work has begun to explore their role in neuronal signaling and neurogenesis (Fuchs and Schwark, 2004 Louvi and Grove 2011).

UniProt: P21932

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma