ADCY3 antibody (AA 950-1030)

Catalog No. ABIN7227220

This Rabbit Polyclonal antibody specifically detects ADCY3 in WB and ELISA. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for ADCY3 antibody (AA 950-1030) (ABIN7227220)

Target: ADCY3 (Adenylate Cyclase 3 (ADCY3))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADCY3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ADCY3 Antibody

Binding Specificity: AA 950-1030

Purpose: Rabbit Anti-ADCY3 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of ADCY3 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human ADCY3 protein at AA range: 950-1030

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ADCY3

Target: ADCY3 (Adenylate Cyclase 3 (ADCY3))

Alternative Name: ADCY3

Background: Adenylate cyclase type 3, ATP pyrophosphate-lyase 3, Adenylate cyclase type III, AC-III, Adenylate cyclase, olfactive type, Adenylyl cyclase 3, AC3ADCY3 (Adenylate Cyclase 3) encodes adenylyl cyclase 3 which is a membrane-associated enzyme and catalyzes the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). This protein appears to be widely expressed in various human tissues and may be involved in a number of physiological and pathophysiological metabolic processes. Two transcript variants encoding different isoforms have been found for ADCY3. ADCY3 is a Protein Coding gene. Among its related pathways are GABAergic synapse and Calcium signaling pathway.

Molecular Weight: 125kD

Gene ID: 109

UniProt: O60266

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma