BST1 antibody

Catalog No. ABIN5540950

This anti-BST1 antibody is a Mouse Monoclonal antibody detecting BST1 in WB, FACS, IP and IHC (fro). Suitable for Human and Primate.

Quick Overview for BST1 antibody (ABIN5540950)

Target: BST1 (Bone Marrow Stromal Cell Antigen 1 (BST1))

Reactivity: Human, Primate

Host: Mouse

Clonality: Monoclonal

Conjugate: This BST1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: SY11B5

Product Details anti-BST1 Antibody

Specificity: This antobody recognizes CD157, an approximately 45 kDa GPI-anchored protein expressed mainly on monocytes, macrophages, granulocytes and bone marrow stromal cells.

Purification: Protein-A affinity chromatography (> 95% pure by SDS-PAGE)

Immunogen: Human CD157

Isotype: IgG1

Application Details

Application Notes: Flow cytometry. Immunoprecipitation. Western blot: non-reducing conditions. Immunohistochemistry (frozen sections).

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 95 % pure by SDS-PAGE) Buffer System: Phosphate buffered saline (PBS) Preservatives: 15 mM sodium azide, approx. pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for BST1

Target: BST1 (Bone Marrow Stromal Cell Antigen 1 (BST1))

Alternative Name: cd157,bst1

Background: CD157 (cADPr hydrolase 2) is a GPI-anchored ectoenzyme possessing ADP-ribosyl cyclase and cyclic ADP-ribose hydrolase activity. It uses NAD and cADP-ribose as substrates. CD157 is expressed on granulocytes, monocytes, macrophages, follicular dendritic cells, bone marrow stromal cells and human umbilical cord vein endothelial cells. In case of rheumatoid arthritis is expression is often higher and it is also differentially expressed in the myeloid leukemias. It may also have a signaling role.

UniProt: Q10588