CEACAM8 antibody

Catalog No. ABIN5541174

The Mouse Monoclonal anti-CEACAM8 antibody is suitable to detect CEACAM8 in samples from Human. It has been validated for FACS and EIA.

Quick Overview for CEACAM8 antibody (ABIN5541174)

Target: CEACAM8 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8 (CEACAM8))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CEACAM8 antibody is un-conjugated

Application: Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Clone: GM2H6

Product Details anti-CEACAM8 Antibody

Specificity: Recognizes CEACAM8 (CD66b/NCA-95).

Purification: Affinity Chromatography on Protein G

Immunogen: Genetic immunisation with cDNA encoding Human CEACAM8.

Isotype: IgG1

Application Details

Application Notes: Cell based ELISA with intakt, transiently transfected cells: 1/200-1/400. Flow cytometry: 1.2 μg/10 6 cells.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Phosphate buffered saline, pH 7.2 without preservatives

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for CEACAM8

Target: CEACAM8 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8 (CEACAM8))

Alternative Name: cd66b,ceacam8

Background: CEA-related cell adhesion molecule 8 (CEACAM8, CD66b) belongs to the carcinoembryonic antigen (CEA) gene family (1,3,4). It encodes a glycosylphosphatidylinositol (GPI)-linked glycoprotein with a Mr of 95,000 which is expressed in cells of the granulocyte-lineage. It is expressed in neutrophils and eosinophils and is characterized as a granulocyte-specific activation antigen. CEACAM8 could serve as a marker for granulocyte activities (2). Like all members of the CEA family, it consists of a single N domain, with structural homology to the immunoglobulin variable domains, followed by two immunoglobulin constant-like A and B do-mains.

UniProt: P31997