CKMT1B antibody (AA 40-417)
Quick Overview for CKMT1B antibody (AA 40-417) (ABIN5541367)
Target
See all CKMT1B AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 40-417
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Purification
- Protein-A affinity chromatography
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Immunogen
- Recombinant human CKMT1A (40-417aa) purified from E. coli
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Isotype
- IgG2b
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Application Notes
- The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.Recommended starting dilution is 1:1000.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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Expiry Date
- 12 months
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- CKMT1B (Creatine Kinase, Mitochondrial 1B (CKMT1B))
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Alternative Name
- ckmt
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Background
- CKMT1A, also known as Creatine kinase, mitochondrial 1A, is 417 amino acid protein. Mitochondrial creatine kinase (MtCK) exists as two isoenzymes, sarcomeric MtCK (CKMT2) and ubiquitous MtCK (CKMT1). It is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis.
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UniProt
- P12532
Target
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