CKMT1B antibody (AA 40-417)

Catalog No. ABIN5541367

Product Details anti-CKMT1B Antibody

Target: CKMT1B (Creatine Kinase, Mitochondrial 1B (CKMT1B))

Binding Specificity: AA 40-417

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CKMT1B antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Purification: Protein-A affinity chromatography

Immunogen: Recombinant human CKMT1A (40-417aa) purified from E. coli

Clone: AT17A2

Isotype: IgG2b

Application Details

Application Notes: The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.Recommended starting dilution is 1:1000.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for CKMT1B

Target: CKMT1B (Creatine Kinase, Mitochondrial 1B (CKMT1B))

Alternative Name: ckmt (CKMT1B Products)

Synonyms: CKMT antibody, CKMT1 antibody, UMTCK antibody, ckmt antibody, ckmt1 antibody, umtck antibody, CKMT1A antibody, creatine kinase, mitochondrial 1B antibody, creatine kinase, mitochondrial 1B S homeolog antibody, creatine kinase, mitochondrial 1B L homeolog antibody, CKMT1B antibody, ckmt1b.S antibody, ckmt1b.L antibody, ckmt1b antibody

Background: CKMT1A, also known as Creatine kinase, mitochondrial 1A, is 417 amino acid protein. Mitochondrial creatine kinase (MtCK) exists as two isoenzymes, sarcomeric MtCK (CKMT2) and ubiquitous MtCK (CKMT1). It is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis.

UniProt: P12532