TIAM1 antibody

Catalog No. ABIN5541409

The Mouse Monoclonal anti-TIAM1 antibody (Clone F5S F6-2) (ABIN5541409) specifically detects TIAM1 in WB and IHC (fro). The antibody is reactive with Human samples.

Quick Overview for TIAM1 antibody (ABIN5541409)

Target: TIAM1 (T-Cell Lymphoma Invasion and Metastasis 1 (TIAM1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TIAM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: F5S F6-2

Product Details anti-TIAM1 Antibody

Specificity: This antibody clone F5S F6.2 is directed against the N-terminal region of Tiam1.

Purification: Purified

Immunogen: T-cell lymphoma invasion and metastasis-inducing protein 1 (Tiam1).

Isotype: IgG2b

Application Details

Application Notes: Western Blot. Immunohistochemistry on Frozen Sections.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Buffer System: PBS Preservatives: 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for TIAM1

Target: TIAM1 (T-Cell Lymphoma Invasion and Metastasis 1 (TIAM1))

Alternative Name: tiam1

Background: Tiam1, also known as T-cell lymphoma invasion and metastasis-inducing protein 1, is a protein that in humans is encoded by the TIAM1 gene. TIAM1 is tightly associate with BAIAP2 as a subunit. It contains one DH (DBL-homology) domain, one PDZ domain, two PH domains and one Ras-binding RBD domain. TIAM1 modulates the activity of Rho GTP-binding proteins and connects extracellular signals to cytoskeletal activities. In addition, TIAM1 activates Rac1, CDC42, and to a lesser extent RhoA. TIAM1 is found in virtually all tumor cell lines examined including B- and T-lymphomas, neuroblastomas, melanomas and carcinomas.

UniProt: Q13009