A2BP1 antibody (N-Term)

Catalog No. ABIN5541450

The Mouse Monoclonal anti-A2BP1 antibody has been validated for WB, ICC and IF. It is suitable to detect A2BP1 in samples from Human, Mouse, Rat and Cow.

Quick Overview for A2BP1 antibody (N-Term) (ABIN5541450)

Target: A2BP1 (Ataxin 2-Binding Protein 1 (A2BP1))

Reactivity: Human, Mouse, Rat, Cow

Host: Mouse

Clonality: Monoclonal

Conjugate: This A2BP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Clone: 1G10

Product Details anti-A2BP1 Antibody

Binding Specificity: N-Term

Specificity: Specific for the ~46/48k FOX1 protein doublet.

Purification: Affinity Chromatography

Immunogen: Recombinant protein taken from the N-terminus of human FOX1 expressed in and purified from E. Coli.

Isotype: IgG1

Application Details

Application Notes: Western Blot: 1/5000. Immunofluorescence: 1/50-1/100.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS Preservatives: 10 mM Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for A2BP1

Target: A2BP1 (Ataxin 2-Binding Protein 1 (A2BP1))

Alternative Name: fox1,a2bp1

Background: FOX1, also known as ataxin-2 binding protein 1 (A2BP1), is a neuron specific RNA-binding protein that has been shown to regulate a wide range of alternative splicing events implicated in neuronal development and maturation including transcription factors and synaptic proteins (Fogel et al., 2012). Defects in FOX1 have also been associated with autism (Martin et al., 2007), attention-deficit hyperactivity disorder (Elia et al., 2010) and schizophrenia (Xu et al., 2008).

UniProt: Q9NWB1