14-3-3 gamma antibody (AA 1-247)

Catalog No. ABIN5541724

The Mouse Monoclonal anti-14-3-3 gamma antibody (Clone AT4B9) (ABIN5541724) specifically detects 14-3-3 gamma in WB and EIA. The antibody is reactive with Human samples.

Quick Overview for 14-3-3 gamma antibody (AA 1-247) (ABIN5541724)

Target: 14-3-3 gamma (YWHAG1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This 14-3-3 gamma antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: AT4B9

Product Details anti-14-3-3 gamma Antibody

Binding Specificity: AA 1-247

Specificity: Recognizes Human 14-3-3 gamma (YWHAG). Other species not tested.

Purification: Protein-A affinity chromatography

Immunogen: Recombinant human 14-3-3 gamma (1-247aa) purified from E. coli.

Isotype: IgG1

Application Details

Application Notes: The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for 14-3-3 gamma

Target: 14-3-3 gamma (YWHAG1)

Alternative Name: 14-3-3 protein gamma

Background: The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, Beta, Gamma, Epsilon, Delta, Zeta, Tau and Eta that have been identified in mammals. The 14-3-3 gamma, a subtype of the 14-3-3 family of proteins, was thought to be brain and neuron-specific. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways.

UniProt: P61981

Pathways: Myometrial Relaxation and Contraction, M Phase