Ficolin 2 antibody

Catalog No. ABIN5541921

The Mouse Monoclonal anti-Ficolin 2 antibody is suitable to detect Ficolin 2 in samples from Human. It has been validated for IP and EIA.

Quick Overview for Ficolin 2 antibody (ABIN5541921)

Target: Ficolin 2 (FCN2) (Ficolin (Collagen/fibrinogen Domain Containing Lectin) 2 (Hucolin) (FCN2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Ficolin 2 antibody is un-conjugated

Application: Immunoprecipitation (IP), Enzyme Immunoassay (EIA)

Clone: GN4

Product Details anti-Ficolin 2 Antibody

Specificity: The monoclonal antibody GN4 recognizes L-Ficolin/P35.

Purification: Purified

Immunogen: L-Ficolin/P35 isolated from Human plasma

Isotype: IgG1

Application Details

Application Notes: Immuno Assays. Immunoprecipitation. For Western blot of Non-Reduced samples we advise to use AM32978PU-N (Clone GN5).

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Buffer System: PBS Stabilizers: 0.1 % BSA

Storage: 4 °C

Storage Comment: Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for Ficolin 2

Target: Ficolin 2 (FCN2) (Ficolin (Collagen/fibrinogen Domain Containing Lectin) 2 (Hucolin) (FCN2))

Alternative Name: ficolin-2

Background: Ficolins are a group of proteins containing both a collagen-like domain and a fibrinogen-like domain. They are found in various tissues. The domain organizations between ficolins and mannose binding lectin (MBL) are similar, although the carbohydrate-binding moieties are different. In man two types of ficolins (Lficolin/ P35 and H-ficolin) are present in serum and one type (M-ficolin) in cells. L-ficolin/P35 (also L-ficolin, ficolin L, EBP-37 or hucolin) is produced primarily by the liver. The association between L-ficolin/P35 and MASPs/sMAP is Ca 2+ -dependent. MASPs in L-ficolin/P35-MASP complexes have proteolytic activities for C4, C2 and C3. L-ficolin/P35 also shows opsonic activity.

UniProt: Q15485

Pathways: Complement System