COTL1 antibody (AA 1-142)

Catalog No. ABIN5541928

The Mouse Monoclonal anti-COTL1 antibody (Clone AT1D6) (ABIN5541928) specifically detects COTL1 in WB and EIA. The antibody is reactive with Human samples.

Quick Overview for COTL1 antibody (AA 1-142) (ABIN5541928)

Target: COTL1 (Coactosin-Like Protein)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This COTL1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: AT1D6

Product Details anti-COTL1 Antibody

Binding Specificity: AA 1-142

Specificity: This antibody recognizes Human COTL1 (coactosin-like 1). Other species not tested.

Purification: Protein-A affinity chromatography

Immunogen: Recombinant human COTL1 (1-142aa) purified from E. coli.

Isotype: IgG2b

Application Details

Application Notes: ELISA. Western blot. Recommended Starting Dilutions: 1/1000.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for COTL1

Target: COTL1 (Coactosin-Like Protein)

Background: COTL1 (coactosin-like 1), also known as CLP, is a 142 amino acid cytoplasmic and cytoskeletal protein that belongs to the actin-binding proteins ADF family and coactosin subfamily. COTL1 is first identified in slime mold and is found at highest levels in kidney, placenta, lung and peripheral blood leukocytes. COTL1 is one of many proteins that participate in regulation of Actin's cytoskeleton through a calcium dependent mechanism, but has not been shown to have a direct effect on Actin depolymerization.

UniProt: Q14019