SSR4 antibody (AA 24-144)

Catalog No. ABIN5542183

Product Details anti-SSR4 Antibody

Target: SSR4 (Signal Sequence Receptor, delta (SSR4))

Binding Specificity: AA 24-144

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SSR4 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Purification: Protein-A affinity chromatography

Immunogen: Recombinant human SSR4 (24-144aa) purified from E. coli

Clone: AT26G5

Isotype: IgG1

Application Details

Application Notes: The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for SSR4

Target: SSR4 (Signal Sequence Receptor, delta (SSR4))

Alternative Name: ssr4,trapd (SSR4 Products)

Synonyms: TRAPD antibody, AW743063 antibody, C78062 antibody, Trap antibody, signal sequence receptor subunit 4 antibody, signal sequence receptor, delta antibody, SSR4 antibody, Ssr4 antibody

Background: SSR4, also called TRAPD, is assumed to be involved in protein secretion. It is located in the Xq28 region, arranged in a compact head-to-head manner with the IDH3G gene. These two genes are driven by a bidirectional promoter located between them, and encode proteins involved in unrelated biochemical pathways located in different compartments of the cell. The nontranscribed intergenic region represents only 133 bp and is embedded in a CpG island. The CpG island functions as a bidirectional promoter to initiate the transcription of both functionally unrelated genes with distinct expression patterns. SSR4 consists of six exons and is approximately 70 kb telomeric to the ALD gene. Although alternative splicing of exon 5 has not been detected in human SSR4, transcript variants missing the region homologous to human exon 5 have been detected in both Xenopus laevis and Mus musculus.

UniProt: P51571