DNMT3A antibody (AA 46-180)

Catalog No. ABIN5542516

The Mouse Monoclonal anti-DNMT3A antibody (Clone 4G5F11) (ABIN5542516) specifically detects DNMT3A in IHC, ELISA and FACS. The antibody is reactive with Human samples.

Quick Overview for DNMT3A antibody (AA 46-180) (ABIN5542516)

Target: DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DNMT3A antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Clone: 4G5F11

Product Details anti-DNMT3A Antibody

Binding Specificity: AA 46-180

Purpose: DNMT3A Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human DNMT3A (AA: 46-180) expressed in E. Coli.

Isotype: IgG2a

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for DNMT3A

Target: DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))

Alternative Name: DNMT3A

Background: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight: 102 kDa

Gene ID: 1788

UniProt: Q9Y6K1