NOTCH3 antibody (AA 47-156)

Catalog No. ABIN5542534

This anti-NOTCH3 antibody is a Mouse Monoclonal antibody detecting NOTCH3 in ELISA. Suitable for Human.

Quick Overview for NOTCH3 antibody (AA 47-156) (ABIN5542534)

Target: NOTCH3 (Notch 3 (NOTCH3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NOTCH3 antibody is un-conjugated

Application: ELISA

Clone: 3E2D9

Product Details anti-NOTCH3 Antibody

Binding Specificity: AA 47-156

Purpose: Notch3 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human Notch3 (AA: 47-156) expressed in E. Coli.

Isotype: IgG2a

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for NOTCH3

Target: NOTCH3 (Notch 3 (NOTCH3))

Alternative Name: Notch3

Background: This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).

Molecular Weight: 243.6 kDa

Gene ID: 4854

UniProt: Q9UM47

Pathways: Notch Signaling