CSF1R antibody (AA 20-152)

Catalog No. ABIN5542590

The Mouse Monoclonal anti-CSF1R antibody has been validated for ELISA and FACS. It is suitable to detect CSF1R in samples from Human.

Quick Overview for CSF1R antibody (AA 20-152) (ABIN5542590)

Target: CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CSF1R antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Clone: 4C9G2

Product Details anti-CSF1R Antibody

Binding Specificity: AA 20-152

Purpose: CSF1R Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CSF1R (AA: 20-152) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for CSF1R

Target: CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

Alternative Name: CSF1R

Background: The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction.

Molecular Weight: 108 kDa

Gene ID: 1436

UniProt: P07333

Pathways: RTK Signaling, Inositol Metabolic Process, Cell-Cell Junction Organization