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Caspase 3 antibody (AA 29-175)

CASP3 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 3D4D10 unconjugated
Catalog No. ABIN5542609
  • Target See all Caspase 3 (CASP3) Antibodies
    Caspase 3 (CASP3)
    Binding Specificity
    • 20
    • 16
    • 16
    • 14
    • 12
    • 12
    • 10
    • 9
    • 9
    • 8
    • 8
    • 7
    • 6
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 29-175
    Reactivity
    • 195
    • 115
    • 72
    • 15
    • 9
    • 8
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Host
    • 207
    • 22
    • 3
    • 2
    • 2
    Mouse
    Clonality
    • 203
    • 32
    Monoclonal
    Conjugate
    • 141
    • 18
    • 17
    • 7
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This Caspase 3 antibody is un-conjugated
    Application
    • 171
    • 96
    • 91
    • 59
    • 41
    • 32
    • 29
    • 27
    • 26
    • 26
    • 25
    • 11
    • 10
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purpose
    CASP3 Antibody
    Purification
    Purified antibody
    Immunogen
    Purified recombinant fragment of human CASP3 (AA: 29-175) expressed in E. Coli.
    Clone
    3D4D10
    Isotype
    IgG1
    Top Product
    Discover our top product CASP3 Primary Antibody
  • Application Notes
    ELISA: 1/10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Target
    Caspase 3 (CASP3)
    Alternative Name
    CASP3 (CASP3 Products)
    Background

    Description: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.

    Aliases: CPP32, SCA-1, CPP32B

    Molecular Weight
    31.6kDa
    Gene ID
    836
    HGNC
    836
    UniProt
    P42574
    Pathways
    Apoptosis, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation
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