CFHR5 antibody (AA 344-569)

Catalog No. ABIN5542639

This anti-CFHR5 antibody is a Mouse Monoclonal antibody detecting CFHR5 in ELISA, IHC, FACS and ICC. Suitable for Human.

Quick Overview for CFHR5 antibody (AA 344-569) (ABIN5542639)

Target: CFHR5 (Complement Factor H-Related 5 (CFHR5))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CFHR5 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: 3E1E10

Product Details anti-CFHR5 Antibody

Binding Specificity: AA 344-569

Purpose: CFHR5 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CFHR5 (AA: 344-569) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for CFHR5

Target: CFHR5 (Complement Factor H-Related 5 (CFHR5))

Alternative Name: CFHR5

Background: This gene is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation. The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS).

Molecular Weight: 64.4 kDa

Gene ID: 81494

UniProt: Q9BXR6