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CFHR5 antibody (AA 344-569)

CFHR5 Reactivity: Human, Mouse WB, ELISA, FACS, IHC, ICC Host: Mouse Monoclonal 3A10A5 unconjugated
Catalog No. ABIN5542640
  • Target See all CFHR5 Antibodies
    CFHR5 (Complement Factor H-Related 5 (CFHR5))
    Binding Specificity
    • 7
    • 6
    • 6
    • 6
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 344-569
    Reactivity
    Human, Mouse
    Host
    • 25
    • 11
    Mouse
    Clonality
    • 26
    • 10
    Monoclonal
    Conjugate
    • 16
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CFHR5 antibody is un-conjugated
    Application
    • 26
    • 18
    • 15
    • 14
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human CFHR5 (AA: 344-569) expressed in E. coli.
    Clone
    3A10A5
    Isotype
    IgG2a
    Top Product
    Discover our top product CFHR5 Primary Antibody
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Target
    CFHR5 (Complement Factor H-Related 5 (CFHR5))
    Alternative Name
    CFHR5 (CFHR5 Products)
    Synonyms
    CFHL5 antibody, CFHR5D antibody, FHR-5 antibody, FHR5 antibody, complement factor H related 5 antibody, CFHR5 antibody
    Background

    Description: This gene is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation. The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS).,

    Aliases: FHR5, CFHL5, FHR-5, CFHR5D

    Molecular Weight
    64.4 kDa
    Gene ID
    81494
    HGNC
    81494
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