MTRF1 antibody (AA 288-437)

Catalog No. ABIN5542689

The Mouse Monoclonal anti-MTRF1 antibody has been validated for WB, ELISA and FACS. It is suitable to detect MTRF1 in samples from Human.

Quick Overview for MTRF1 antibody (AA 288-437) (ABIN5542689)

Target: MTRF1 (Mitochondrial Translational Release Factor 1 (MTRF1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MTRF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Clone: 4F9H12

Product Details anti-MTRF1 Antibody

Binding Specificity: AA 288-437

Purpose: RF1 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human RF1 (AA: 288-437) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for MTRF1

Target: MTRF1 (Mitochondrial Translational Release Factor 1 (MTRF1))

Alternative Name: RF1

Background: This gene encodes a class-1 polypeptide chain release factor. The encoded protein plays an essential role in directing termination of mRNA translation from the termination codons UAA, UAG and UGA. This protein is a component of the SURF complex which promotes degradation of prematurely terminated mRNAs via the mechanism of nonsense-mediated mRNA decay (NMD). Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 6, 7, and X.

Molecular Weight: 49 kDa

UniProt: P62495