Glutaminase Kidney Isoform (C-Term) antibody

Catalog No. ABIN5553836

This Rabbit Polyclonal antibody specifically detects Glutaminase Kidney Isoform in EIA, IHC (p) and WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for Glutaminase Kidney Isoform (C-Term) antibody (ABIN5553836)

Target: Glutaminase Kidney Isoform

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Application: Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Product Details

Binding Specificity: C-Term

Specificity: This antibody recognizes GLS.

Purification: Affinity Chromatography on Protein A followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 523-553 from the C-terminal region of Human GLS Genename: GLS

Application Details

Application Notes: WB, E
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details

Target: Glutaminase Kidney Isoform

Background: Sahai (1983) demonstrated phosphate-activated glutaminase (EC 3.5.1.2) in human platelets. It is the major enzyme yielding glutamate from glutamine. Significance of the enzyme derives from its possible implication in behavior disturbances in which glutamate acts as a neurotransmitter(Prusiner, 1981). High heritability of platelet glutaminase was indicated by studies of Sahai and Vogel (1983) [PubMed 6682827] who found an intraclass correlation coefficient of 0.96 for monozygotic twins and 0.53 for dizygotic twins.Synonyms: GLS, GLS1, K-glutaminase, KIAA0838, L-glutamine amidohydrolase

Gene ID: 2744

NCBI Accession: NP_055720

UniProt: O94925