Recombinant KRT17 antibody (N-Term)
Quick Overview for Recombinant KRT17 antibody (N-Term) (ABIN5557441)
Target
See all KRT17 AntibodiesAntibody Type
Reactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Purpose
- Cytokeratin 17 Recombinant Antibody
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Cross-Reactivity
- Human, Mouse, Rat
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Purification
- Purified by Protein A.
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Immunogen
- Recombinant human Cytokeratin 17 protein, around N-terminal 100aa.
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Isotype
- IgG
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Application Notes
- WB(1:300-5000), IHC-P(1:200-400), IHC-F(1:100-500), IF(1:50-100), Flow-Cyt(1 μg/Test), ICC/IF(1:50-100)
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Expiry Date
- 12 months
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- KRT17 (Keratin 17 (KRT17))
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Alternative Name
- Cytokeratin 17
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Background
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Synonyms: 39.1, CK 17, Cytokeratin17, K17, Keratin 17, Keratin type I cytoskeletal 17, Keratin17, KRT 17, KRT17, KRT17 protein, PC, PC2, PCHC1, K1C17_HUMAN.
Background: The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21.
This gene encodes the type I intermediate filament chain keratin 17, expressed in nail bed, hair follicle, sebaceous glands, and other epidermal appendages. Mutations in this gene lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex. [provided by RefSeq, Aug 2008]. -
Gene ID
- 3872
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UniProt
- Q04695
Target
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