IRGM antibody

Catalog No. ABIN5557540

The Mouse Monoclonal anti-IRGM antibody has been validated for WB. It is suitable to detect IRGM in samples from Mouse.

Quick Overview for IRGM antibody (ABIN5557540)

Target: IRGM (Immunity-Related GTPase Family, M (IRGM))

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This IRGM antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 3T5

Product Details anti-IRGM Antibody

Cross-Reactivity: Mouse

Purification: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Immunogen: Purified His-tagged Mouse Irgm1 protein was used to produced this monoclonal antibody.

Isotype: IgM

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for IRGM

Target: IRGM (Immunity-Related GTPase Family, M (IRGM))

Alternative Name: Irgm1

Background:

Synonyms: Ifi1, Irgm, Iigp3, Iipg3, Ifggd3, LRG-47, Immunity-related GTPase family M protein 1, Interferon-inducible GTPase 3, Interferon-inducible protein 1, LPS-stimulated RAW 264.7 macrophage protein 47, Irgm1

Background: Putative GTPase which is required for IFNG-mediated clearance of acute protozoan and bacterial infections. Functions in innate immune response probably through regulation of autophagy. May regulate proinflammatory cytokine production and prevent endotoxemia upon infection. Required for macrophage motility and possibly also for adhesion.

Gene ID: 15944

UniProt: Q60766