CD31 antibody

Catalog No. ABIN5563928

This Mouse Monoclonal antibody specifically detects CD31 in FACS, IHC and IP. It exhibits reactivity toward Human.

Quick Overview for CD31 antibody (ABIN5563928)

Target: CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD31 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Grade: GMP Grade

Clone: JC70

Product Details anti-CD31 Antibody

Purpose: CD31 Unconjugated Antibody

Characteristics: The clone JC70, recognizes a 130-140 kD type I transmembrane glycoprotein known as CD31. CD31 is also known as PECAM-1 (Platelet Endothelial Cell Adhesion Molecule-1) and is a member of the immunoglobulin (Ig) superfamily. It is expressed on the surface of circulating platelets, monocytes, neutrophils, particular T-cell subsets, and is a component of the endothelial cell intercellular junction. CD31 is implicated in several functions, including transendothelial migration of leukocytes, angiogenesis, integrin activation, etc.

Purification: Purified

Purity: >95 %

Immunogen: Cell membrane preparation from the spleen of a patient with hairy cell leukaemia

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for CD31

Target: CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Alternative Name: CD31

UniProt: P16284

Pathways: Regulation of Actin Filament Polymerization