SFMBT1 antibody (C-Term)

Catalog No. ABIN5563984

Cited in 1 publication. The Rabbit Polyclonal anti-SFMBT1 antibody (ABIN5563984) specifically detects SFMBT1 in WB, IP, ChIP, IF and ChIP-seq. The antibody is reactive with Mouse samples.

Quick Overview for SFMBT1 antibody (C-Term) (ABIN5563984)

Target: SFMBT1 (Scm-Like with Four Mbt Domains 1 (SFMBT1))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SFMBT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP), Immunofluorescence (IF), ChIP DNA-Sequencing (ChIP-seq)

Product Details anti-SFMBT1 Antibody

Binding Specificity: C-Term

Purpose: SFMBT1 antibody (pAb)

Specificity: Mouse

Purification: Affinity Purified

Immunogen: This antibody was raised against a peptide within the C-terminal region of mouse SFMBT1.

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2,500 dilution

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Storage: -20 °C

Storage Comment: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Expiry Date: 24 months

References for anti-SFMBT1 antibody (ABIN5563984)

Zhang, Bonasio, Strino, Kluger, Holloway, Modzelewski, Cohen, Reinberg: "SFMBT1 functions with LSD1 to regulate expression of canonical histone genes and chromatin-related factors." in: Genes & development, Vol. 27, Issue 7, pp. 749-66, (2013) (PubMed).

Target Details for SFMBT1

Target: SFMBT1 (Scm-Like with Four Mbt Domains 1 (SFMBT1))

Alternative Name: SFMBT1

Background: SFMBT1 (Scm-Like With Four Mbt Domains 1) is a histone-binding protein, which is part of various corepressor complexes. Mediates the recruitment of corepressor complexes to target genes, followed by chromatin compaction and repression of transcription. Plays a role during myogenesis: required for the maintenance of undifferentiated states of myogenic progenitor cells via interaction with MYOD1. Interaction with MYOD1 leads to the recruitment of associated corepressors and silencing of MYOD1 target genes. Part of the SLC complex in germ cells, where it may play a role during spermatogenesis.

Molecular Weight: 110 kDa

NCBI Accession: NP_062333