KALRN antibody (C-Term)

Catalog No. ABIN559714

This Rabbit Polyclonal antibody specifically detects KALRN in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for KALRN antibody (C-Term) (ABIN559714)

Target: KALRN (Kalirin, RhoGEF Kinase (KALRN))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KALRN antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-KALRN Antibody

Binding Specificity: C-Term

Specificity: Reacts with the human 192 kDa Kalirin protein

Cross-Reactivity: Mouse (Murine)

Cross-Reactivity (Details): May cross-react with mouse protein due to sequence homology.

Purification: Antiserum

Immunogen: Synthetic peptide derived from Cter domain of human Kalirin protein

Isotype: IgG

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Storage: 4 °C/-20 °C

Storage Comment: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Expiry Date: 24 months

Target Details for KALRN

Target: KALRN (Kalirin, RhoGEF Kinase (KALRN))

Alternative Name: Kalirin

Background: Promotes the exchange of GDP by GTP. Activates specific Rho GTPase family members, thereby inducing various signaling mechanisms that regulate neuronal shape, growth, and plasticity, through their effects on the actin cytoskeleton. Induces lamellipodia independent of its GEF activity

Pathways: Neurotrophin Signaling Pathway