ALAS2 antibody (AA 1-100)

Catalog No. ABIN559841

The Mouse Monoclonal anti-ALAS2 antibody has been validated for WB and ELISA. It is suitable to detect ALAS2 in samples from Human. There are 2+ publications available.

Quick Overview for ALAS2 antibody (AA 1-100) (ABIN559841)

Target: ALAS2 (Aminolevulinate, delta-, Synthase 2 (ALAS2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ALAS2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 6C1

Product Details anti-ALAS2 Antibody

Binding Specificity: AA 1-100

Purpose: Mouse monoclonal antibody raised against a partial recombinant ALAS2.

Sequence: MVTAAMLLQC CPVLARGPTS LLGKVVKTHQ FLFGIGRCPI LATQGPNCSQ IHLKATKAGG DSPSWAKGHC PFMLSELQDG KSKIVQKAAP EVQEDVKAFK

Cross-Reactivity: Human, Mouse

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: ALAS2 (NP_000023, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-ALAS2 antibody (ABIN559841)

Ma, Chen, Wu, Zhao, Yu, Yu, Zhang: "Emodin can induce K562 cells to erythroid differentiation and improve the expression of globin genes." in: Molecular and cellular biochemistry, Vol. 382, Issue 1-2, pp. 127-36, (2013) (PubMed).

Zhang, Shen, Liu, Wang, Zhao, Yu, Zhang: "Hypoxic induction of human erythroid-specific ?-aminolevulinate synthase mediated by hypoxia-inducible factor 1." in: Biochemistry, Vol. 50, Issue 7, pp. 1194-202, (2011) (PubMed).

Target Details for ALAS2

Target: ALAS2 (Aminolevulinate, delta-, Synthase 2 (ALAS2))

Alternative Name: ALAS2

Background: Full Gene Name: aminolevulinate, delta-, synthase 2
Synonyms: ALAS-E,ALASE,ANH1,ASB,FLJ93603,XLSA

Gene ID: 212

NCBI Accession: NM_000032

Pathways: Transition Metal Ion Homeostasis