Survivin antibody (AA 1-100)

Catalog No. ABIN559893

Cited in 2+ publications. The Mouse Monoclonal anti-Survivin antibody (Clone 5B10) (ABIN559893) specifically detects Survivin in WB, ELISA, IF, IP and RNAi. The antibody is reactive with Human samples.

Quick Overview for Survivin antibody (AA 1-100) (ABIN559893)

Target: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Survivin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), RNA Interference (RNAi)

Clone: 5B10

Product Details anti-Survivin Antibody

Binding Specificity: AA 1-100

Purpose: Mouse monoclonal antibody raised against a partial recombinant BIRC5.

Sequence: MGAPTLPPAW QPFLKDHRIS TFKNWPFLEG CACTPERMAE AGFIHCPTEN EPDLAQCFFC FKELEGWEPD DDPIEEHKKH SSGCAFLSVK KQFEELTLGE

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: BIRC5 (NP_001159, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-Survivin antibody (ABIN559893)

Horowitz, Ajayi, Kulasekaran, Rogers, White, Townsend, White, Nho, Higgins, Huang, Sisson: "Survivin expression induced by endothelin-1 promotes myofibroblast resistance to apoptosis." in: The international journal of biochemistry & cell biology, Vol. 44, Issue 1, pp. 158-69, (2011) (PubMed).

Yamazaki, Fujiwara, Yukinaga, Ebisuya, Shiki, Kurihara, Kioka, Kambe, Nagao, Nishida, Masuda: "The closely related RNA helicases, UAP56 and URH49, preferentially form distinct mRNA export machineries and coordinately regulate mitotic progression." in: Molecular biology of the cell, Vol. 21, Issue 16, pp. 2953-65, (2010) (PubMed).

Target Details for Survivin

Target: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Alternative Name: BIRC5

Background: Full Gene Name: baculoviral IAP repeat-containing 5
Synonyms: API4,EPR-1

Gene ID: 332

NCBI Accession: NM_001168

Pathways: Apoptosis, Cell Division Cycle, Nuclear Hormone Receptor Binding