BLK antibody (AA 1-90)

Catalog No. ABIN560064

This anti-BLK antibody is a Mouse Monoclonal antibody detecting BLK in WB and ELISA. Suitable for Human. This Primary Antibody has been cited in 2+ publications.

Quick Overview for BLK antibody (AA 1-90) (ABIN560064)

Target: BLK (B Lymphoid Tyrosine Kinase (BLK))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BLK antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 7A12

Product Details anti-BLK Antibody

Binding Specificity: AA 1-90

Purpose: Mouse monoclonal antibody raised against a partial recombinant BLK.

Sequence: MGLVSSKKPD KEKPIKEKDK GQWSPLKVSA QDKDAPPLPP LVVFNHLTPP PPDEHLDEDK HFVVALYDYT AMNDRDLQML KGEKLQVLKG

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: BLK (AAH07371, 1 a.a. ~ 90 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-BLK antibody (ABIN560064)

Bernal-Quirós, Wu, Alarcón-Riquelme, Castillejo-López: "BANK1 and BLK act through phospholipase C gamma 2 in B-cell signaling." in: PLoS ONE, Vol. 8, Issue 3, pp. e59842, (2013) (PubMed).

Castillejo-López, Delgado-Vega, Wojcik, Kozyrev, Thavathiru, Wu, Sánchez, Pöllmann, López-Egido, Fineschi, Domínguez, Lu, James, Merrill, Kelly, Kaufman, Moser, Gilkeson, Frostegård, Pons-Estel et al.: "Genetic and physical interaction of the B-cell systemic lupus erythematosus-associated genes BANK1 and BLK. ..." in: Annals of the rheumatic diseases, Vol. 71, Issue 1, pp. 136-42, (2011) (PubMed).

Target Details for BLK

Target: BLK (B Lymphoid Tyrosine Kinase (BLK))

Alternative Name: BLK

Background: Full Gene Name: B lymphoid tyrosine kinase
Synonyms: MGC10442

Gene ID: 640

Pathways: Positive Regulation of Peptide Hormone Secretion, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling