CBR1 antibody (AA 1-277)
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- Target See all CBR1 Antibodies
- CBR1 (Carbonyl Reductase 1 (CBR1))
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Binding Specificity
- AA 1-277
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CBR1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Purpose
- Mouse monoclonal antibody raised against a full length recombinant CBR1.
- Sequence
- MSSGIHVALV TGGNKGIGLA IVRDLCRLFS GDVVLTARDV TRGQAAVQQL QAEGLSPRFH QLDIDDLQSI RALRDFLRKE YGGLDVLVNN AGIAFKVADP TPFHIQAEVT MKTNFFGTRD VCTELLPLIK PQGRVVNVSS IMSVRALKSC SPELQQKFRS ETITEEELVG LMNKFVEDTK KGVHQKEGWP SSAYGVTKIG VTVLSRIHAR KLSEQRKGDK ILLNACCPGW VRTDMAGPKA TKSPEEGAET PVYLALLPPD AEGPHGQFVS EKRVEQW
- Cross-Reactivity
- Human
- Characteristics
- Antibody Reactive Against Recombinant Protein.
- Immunogen
- CBR1 (AAH02511.1, 1 a.a. ~ 277 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Clone
- 4G11-1C7
- Isotype
- IgG2a
- Top Product
- Discover our top product CBR1 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Buffer
- In 1x PBS, pH 7.4
- Handling Advice
- Aliquot to avoid repeated freezing and thawing.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Carbonyl reductase 1 protects pancreatic β-cells against oxidative stress-induced apoptosis in glucotoxicity and glucolipotoxicity." in: Free radical biology & medicine, Vol. 49, Issue 10, pp. 1522-33, (2010) (PubMed).
: "Two nonsynonymous single nucleotide polymorphisms of human carbonyl reductase 1 demonstrate reduced in vitro metabolism of daunorubicin and doxorubicin." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 37, Issue 5, pp. 1107-14, (2009) (PubMed).
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Carbonyl reductase 1 protects pancreatic β-cells against oxidative stress-induced apoptosis in glucotoxicity and glucolipotoxicity." in: Free radical biology & medicine, Vol. 49, Issue 10, pp. 1522-33, (2010) (PubMed).
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- Target
- CBR1 (Carbonyl Reductase 1 (CBR1))
- Alternative Name
- CBR1 (CBR1 Products)
- Background
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Full Gene Name: carbonyl reductase 1
Synonyms: CBR,SDR21C1,hCBR1 - Gene ID
- 873
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