EGFR antibody (AA 26-125)
Quick Overview for EGFR antibody (AA 26-125) (ABIN560704)
Target
See all EGFR AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 26-125
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Purpose
- Mouse polyclonal antibody raised against a partial recombinant EGFR.
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Sequence
- EEKKVCQGTS NKLTQLGTFE DHFLSLQRMF NNCEVVLGNL EITYVQRNYD LSFLKTIQEV AGYVLIALNT VERIPLENLQ IIRGNMYYEN SYALAVLSNY
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Cross-Reactivity
- Human
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Characteristics
- Antibody Reactive Against Recombinant Protein.
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Immunogen
- EGFR (NP_005219, 26 a.a. ~ 125 a.a) partial recombinant protein with GST tag.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 50 % glycerol
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Handling Advice
- Aliquot to avoid repeated freezing and thawing.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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: "Integrin alphavbeta3 mediates upregulation of epidermal growth-factor receptor expression and activity in human ovarian cancer cells." in: The international journal of biochemistry & cell biology, Vol. 40, Issue 12, pp. 2746-61, (2008) (PubMed).
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: "Integrin alphavbeta3 mediates upregulation of epidermal growth-factor receptor expression and activity in human ovarian cancer cells." in: The international journal of biochemistry & cell biology, Vol. 40, Issue 12, pp. 2746-61, (2008) (PubMed).
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- EGFR (Epidermal Growth Factor Receptor (EGFR))
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Alternative Name
- EGFR
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Background
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Full Gene Name: epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
Synonyms: ERBB,ERBB1,HER1,PIG61,mENA -
Gene ID
- 1956
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NCBI Accession
- NM_005228
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Pathways
- NF-kappaB Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins
Target
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