EGR1 antibody (AA 444-543)

Catalog No. ABIN560707

This Mouse Monoclonal antibody specifically detects EGR1 in WB, ELISA, IF and IHC (p). It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for EGR1 antibody (AA 444-543) (ABIN560707)

Target: EGR1 (Early Growth Response 1 (EGR1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This EGR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 6E8

Product Details anti-EGR1 Antibody

Binding Specificity: AA 444-543

Purpose: Mouse monoclonal antibody raised against a partial recombinant EGR1.

Sequence: SPVATSYPSP VTTSYPSPAT TSYPSPVPTS FSSPGSSTYP SPVHSGFPSP SVATTYSSVP PAFPAQVSSF PSSAVTNSFS ASTGLSDMTA TFSPRTIEIC

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: EGR1 (NP_001955, 444 a.a. ~ 543 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-EGR1 antibody (ABIN560707)

Lasham, Mehta, Fitzgerald, Woolley, Hearn, Hurley, Ruza, Algie, Shelling, Braithwaite, Print: "A novel EGR-1 dependent mechanism for YB-1 modulation of paclitaxel response in a triple negative breast cancer cell line." in: International journal of cancer, Vol. 139, Issue 5, pp. 1157-70, (2016) (PubMed).

Bupha-Intr, Holmes, Janssen: "Induction of hypertrophy in vitro by mechanical loading in adult rabbit myocardium." in: American journal of physiology. Heart and circulatory physiology, Vol. 293, Issue 6, pp. H3759-67, (2007) (PubMed).

Target Details for EGR1

Target: EGR1 (Early Growth Response 1 (EGR1))

Alternative Name: EGR1

Background: Full Gene Name: early growth response 1
Synonyms: AT225,G0S30,KROX-24,NGFI-A,TIS8,ZIF-268,ZNF225

Gene ID: 1958

NCBI Accession: NM_001964

Pathways: Regulation of Carbohydrate Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity