Fatty Acid Synthase antibody (AA 1-439)

Catalog No. ABIN560848

This Mouse Monoclonal antibody specifically detects Fatty Acid Synthase in WB, IP, ELISA, IF and IHC (p). It exhibits reactivity toward Human and has been mentioned in 3+ publications.

Quick Overview for Fatty Acid Synthase antibody (AA 1-439) (ABIN560848)

Target: Fatty Acid Synthase (FASN)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Fatty Acid Synthase antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 3F2-1F3

Product Details anti-Fatty Acid Synthase Antibody

Binding Specificity: AA 1-439

Purpose: Mouse monoclonal antibody raised against a full length recombinant FASN.

Sequence: MSTNDTIVSG TLPQRMASCL EVLDLFLNQP HMVLSSFVLA EKAAAYRDRD SQRDLVEAVA HILGIRDLAA VNLDSSLADL GLDSLMSVEV RQTLERELNL VLSVREVRQL TLRKLQELSS KADEASELAC PTPKEDGLAQ QQTQLNLRSL LVNPEGPTLM RLNSVQSSER PLFLVHPIEG STTVFHSLAS GLSIPTYGLQ CTRAAPLDSI HSLAAYYIDC IRQVQPEGPY RVAGYSYGAC VAFEMCSQLQ AQQSPAPTHN SLFLFDGSPT YVLAYTQSYR AKLTPGCEAE AETEAICFFV QQFTDMEHNR VLEALLPLKG LEERVAAAVD LIIKSHQGLD RQELSFAARS FYYKLRAAEQ YTPKAKYHGN VMLLRAKTGG AYGEDLGADY NLSQVCDGKV SVHVIEGDHR TLLEGSGLES IISIIHSSLA EPRVSVREG

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: FASN (AAH07909, 1 a.a. ~ 439 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-Fatty Acid Synthase antibody (ABIN560848)

Meller, Bicker, Montani, Ikenberg, Rostamzadeh, Sailer, Wild, Dietrich, Uhl, Sulser, Moch, Gorr, Stephan, Jung, Hankeln, Kristiansen: "Myoglobin expression in prostate cancer is correlated to androgen receptor expression and markers of tumor hypoxia." in: Virchows Archiv : an international journal of pathology, Vol. 465, Issue 4, pp. 419-27, (2014) (PubMed).

Gorr, Wichmann, Pilarsky, Theurillat, Fabrizius, Laufs, Bauer, Koslowski, Horn, Burmester, Hankeln, Kristiansen: "Old proteins - new locations: myoglobin, haemoglobin, neuroglobin and cytoglobin in solid tumours and cancer cells." in: Acta physiologica (Oxford, England), Vol. 202, Issue 3, pp. 563-81, (2011) (PubMed).

Kristiansen, Rose, Geisler, Fritzsche, Gerhardt, Lüke, Ladhoff, Knüchel, Dietel, Moch, Varga, Theurillat, Gorr, Dahl: "Endogenous myoglobin in human breast cancer is a hallmark of luminal cancer phenotype." in: British journal of cancer, Vol. 102, Issue 12, pp. 1736-45, (2010) (PubMed).

Target Details for Fatty Acid Synthase

Target: Fatty Acid Synthase (FASN)

Alternative Name: FASN

Background: Full Gene Name: fatty acid synthase
Synonyms: FAS,MGC14367,MGC15706,OA-519,SDR27X1

Gene ID: 2194

Pathways: AMPK Signaling