FOXC2 antibody (AA 421-501)

Catalog No. ABIN560913

Cited in 3+ publications. The Mouse Monoclonal anti-FOXC2 antibody (Clone 2H3) (ABIN560913) specifically detects FOXC2 in ELISA, IF and IHC (p). The antibody is reactive with Human samples.

Quick Overview for FOXC2 antibody (AA 421-501) (ABIN560913)

Target: FOXC2 (Forkhead Box C2 (MFH-1, Mesenchyme Forkhead 1) (FOXC2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FOXC2 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 2H3

Product Details anti-FOXC2 Antibody

Binding Specificity: AA 421-501

Purpose: Mouse monoclonal antibody raised against a partial recombinant FOXC2.

Sequence: AASWYLNHSG DLNHLPGHTF AAQQQTFPNV REMFNSHRLG IENSTLGESQ VSGNASCQLP YRSTPPLYRH AAPYSYDCTK Y

Cross-Reactivity: Human, Rat

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: FOXC2 (NP_005242.1, 421 a.a. ~ 501 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2b

Application Details

Application Notes: Suggested Applications*:elisa,western blotting,immunohistochemistry (paraffin-embedded sections),immunofluorescence
*We do not guarantee this product working for suggested applications.
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-FOXC2 antibody (ABIN560913)

Imayama, Yamada, Yanamoto, Naruse, Matsushita, Takahashi, Seki, Fujita, Ikeda, Umeda: "FOXC2 expression is associated with tumor proliferation and invasion potential in oral tongue squamous cell carcinoma." in: Pathology oncology research : POR, Vol. 21, Issue 3, pp. 783-91, (2015) (PubMed).

Yu, Chen, Chen, Cheng, Hsu, Chang, Chen, Jan, Hsiao, Chang, Liu, Jeng, Wu, Huang, Su, Hung, Chien, Chen, Kuo, Su: "MiR-520h-mediated FOXC2 regulation is critical for inhibition of lung cancer progression by resveratrol." in: Oncogene, Vol. 32, Issue 4, pp. 431-43, (2013) (PubMed).

Nishida, Mimori, Yokobori, Sudo, Tanaka, Shibata, Ishii, Doki, Mori: "FOXC2 is a novel prognostic factor in human esophageal squamous cell carcinoma." in: Annals of surgical oncology, Vol. 18, Issue 2, pp. 535-42, (2011) (PubMed).

Target Details for FOXC2

Target: FOXC2 (Forkhead Box C2 (MFH-1, Mesenchyme Forkhead 1) (FOXC2))

Alternative Name: FOXC2

Background: Full Gene Name: forkhead box C2 (MFH-1, mesenchyme forkhead 1)
Synonyms: FKHL14,LD,MFH-1,MFH1

Gene ID: 2303

NCBI Accession: NM_005251