MTOR antibody (AA 1521-1620)

Catalog No. ABIN560949

The Mouse Monoclonal anti-MTOR antibody (Clone 2C5) (ABIN560949) specifically detects MTOR in ELISA and PLA. The antibody is reactive with Human samples.

Quick Overview for MTOR antibody (AA 1521-1620) (ABIN560949)

Target: MTOR (mTOR) (Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MTOR antibody is un-conjugated

Application: ELISA, Proximity Ligation Assay (PLA)

Clone: 2C5

Product Details anti-MTOR Antibody

Binding Specificity: AA 1521-1620

Purpose: Mouse monoclonal antibody raised against a partial recombinant FRAP1.

Sequence: WGLGQWDSME EYTCMIPRDT HDGAFYRAVL ALHQDLFSLA QQCIDKARDL LDAELTAMAG ESYSRAYGAM VSCHMLSELE EVIQYKLVPE RREIIRQIWW

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: MTOR (NP_004949, 1521 a.a. ~ 1620 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Target Details for MTOR

Target: MTOR (mTOR) (Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR))

Alternative Name: MTOR

Background: Full Gene Name: mechanistic target of rapamycin
Synonyms: FRAP,FRAP1,FRAP2,RAFT1,RAPT1

Gene ID: 2475

NCBI Accession: NM_004958

Pathways: PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, BCR Signaling, Warburg Effect