GBE1 antibody (AA 605-702)

Catalog No. ABIN561010

This Mouse Polyclonal antibody specifically detects GBE1 in WB and ELISA. It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for GBE1 antibody (AA 605-702) (ABIN561010)

Target: GBE1 (Glucan (1,4-alpha-), Branching Enzyme 1 (GBE1))

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This GBE1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GBE1 Antibody

Binding Specificity: AA 605-702

Purpose: Mouse polyclonal antibody raised against a partial recombinant GBE1.

Sequence: SEKHEGNKII AFERAGLLFI FNFHPSKSYT DYRVGTALPG KFKIVLDSDA AEYGGHQRLD HSTDFFSEAF EHNGRPYSLL VYIPSRVALI LQNVDLPN

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: GBE1 (NP_000149, 605 a.a. ~ 702 a.a) partial recombinant protein with GST tag.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 50 % glycerol

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-GBE1 antibody (ABIN561010)

Irimia, Tagliabracci, Meyer, Segvich, DePaoli-Roach, Roach: "Muscle glycogen remodeling and glycogen phosphate metabolism following exhaustive exercise of wild type and laforin knockout mice." in: The Journal of biological chemistry, (2015) (PubMed).

Kakhlon, Glickstein, Feinstein, Liu, Baba, Terashima, Akman, Dimauro, Lossos: "Polyglucosan neurotoxicity caused by glycogen branching enzyme deficiency can be reversed by inhibition of glycogen synthase." in: Journal of neurochemistry, Vol. 127, Issue 1, pp. 101-13, (2013) (PubMed).

Target Details for GBE1

Target: GBE1 (Glucan (1,4-alpha-), Branching Enzyme 1 (GBE1))

Alternative Name: GBE1

Background: Full Gene Name: glucan (1,4-alpha-), branching enzyme 1
Synonyms: GBE

Gene ID: 2632

NCBI Accession: NM_000158

Pathways: Cellular Glucan Metabolic Process