GOT2 antibody (AA 331-430)

Catalog No. ABIN561090

Cited in 2+ publications. The Mouse Polyclonal anti-GOT2 antibody (ABIN561090) specifically detects GOT2 in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for GOT2 antibody (AA 331-430) (ABIN561090)

Target: GOT2 (Glutamic-Oxaloacetic Transaminase 2, Mitochondrial (Aspartate Aminotransferase 2) (GOT2))

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This GOT2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GOT2 Antibody

Binding Specificity: AA 331-430

Purpose: Mouse polyclonal antibody raised against a partial recombinant GOT2.

Sequence: LNTPDLRKQW LQEVKGMADR IIGMRTQLVS NLKKEGSTHN WQHITDQIGM FCFTGLKPEQ VERLIKEFSI YMTKDGRISV AGVTSSNVGY LAHAIHQVTK

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: GOT2 (NP_002071, 331 a.a. ~ 430 a.a) partial recombinant protein with GST tag.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 50 % glycerol

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-GOT2 antibody (ABIN561090)

Cooper, Hanigan et al.: "Food and Chemical Toxicology, 2011, 'Possible role of cysteine-S-conjugate ?-lyase in species differences in cisplatin nephrotoxicity', R. Katayama, S. Nagata, H. Iida, N. Yamagishi, T. Yamashita, K. ..." in: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 49, Issue 12, pp. 3279-80, (2011) (PubMed).

Orr, Li, Wang, Li, Wang, Rong, Xu, Mastroberardino, Greenamyre, Li: "N-terminal mutant huntingtin associates with mitochondria and impairs mitochondrial trafficking." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 28, Issue 11, pp. 2783-92, (2008) (PubMed).

Target Details for GOT2

Target: GOT2 (Glutamic-Oxaloacetic Transaminase 2, Mitochondrial (Aspartate Aminotransferase 2) (GOT2))

Alternative Name: GOT2

Background: Full Gene Name: glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)
Synonyms: FLJ40994,KAT4,KATIV,mitAAT

Gene ID: 2806

NCBI Accession: NM_002080

Pathways: Monocarboxylic Acid Catabolic Process