GOT2 antibody (AA 30-430)

Catalog No. ABIN5776157

The Mouse Monoclonal anti-GOT2 antibody (Clone AT8B11) (ABIN5776157) specifically detects GOT2 in WB, ELISA, ICC, FACS and IF. The antibody is reactive with Human samples.

Quick Overview for GOT2 antibody (AA 30-430) (ABIN5776157)

Target: GOT2 (Glutamic-Oxaloacetic Transaminase 2, Mitochondrial (Aspartate Aminotransferase 2) (GOT2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GOT2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: AT8B11

Product Details anti-GOT2 Antibody

Binding Specificity: AA 30-430

Purpose: Human GOT2 antibody

Immunogen: Recombinant human GOT2 (30-430aa) purified from E.coli

Isotype: IgG3 kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing cycles

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for GOT2

Target: GOT2 (Glutamic-Oxaloacetic Transaminase 2, Mitochondrial (Aspartate Aminotransferase 2) (GOT2))

Alternative Name: GOT2

Background: Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. Also, GOT2 is a major participant in the malate-aspartate shuttle, which is a passage from the cytosol to the mitochondria. The two enzymes are homodimeric and show close homology. GOT2 has been seen to have a role in cell proliferation, especially in terms of tumor growth.

NCBI Accession: NP_002071

Pathways: Monocarboxylic Acid Catabolic Process