PD-1 antibody (AA 21-170)

Catalog No. ABIN5611150

This anti-PD-1 antibody is a Mouse Monoclonal antibody detecting PD-1 in FACS, WB and ELISA. Suitable for Human.

Quick Overview for PD-1 antibody (AA 21-170) (ABIN5611150)

Target: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PD-1 antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), ELISA

Clone: 1D6F6

Product Details anti-PD-1 Antibody

Binding Specificity: AA 21-170

Purpose: PD1 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human PD1 (AA: 21-170) expressed in HEK293 cells.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for PD-1

Target: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Alternative Name: PD1

Background: This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.

Molecular Weight: 31.6KD

Gene ID: 5133

UniProt: Q15116

Pathways: Cancer Immune Checkpoints