BCMA antibody

Catalog No. ABIN5611185

Product Details anti-BCMA Antibody

Target: BCMA (TNFRSF17) (Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BCMA antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Purpose: CD269 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human BCMA (AA: QMAGQCSQNEYFDSLc) expressed in E. Coli.

Clone: 1D12G9

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for BCMA

Target: BCMA (TNFRSF17) (Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17))

Alternative Name: CD269 (TNFRSF17 Products)

Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.

Molecular Weight: 20.2 kDa

UniProt: Q02223