GRF2 antibody (AA 1-110)

Catalog No. ABIN561125

There is 1 publication for this product available. The Mouse Monoclonal anti-GRF2 antibody is suitable to detect GRF2 in samples from Human. It has been validated for WB and ELISA.

Quick Overview for GRF2 antibody (AA 1-110) (ABIN561125)

Target: GRF2 (RAPGEF1) (Rap Guanine Nucleotide Exchange Factor (GEF) 1 (RAPGEF1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GRF2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 3D10

Product Details anti-GRF2 Antibody

Binding Specificity: AA 1-110

Purpose: Mouse monoclonal antibody raised against a partial recombinant RAPGEF1.

Sequence: MGNAIEKQKP LKRSHLYPWK QDSQRSHLSS FTMKLMDKFH SPKIKRTPSK KGKPAEVSVK IPEKPVNKEA TDRFLPEGYP LPLDLEQQAV EFMSTSAVAS RSQRQKNLSW

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: RAPGEF1 (AAH41710, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-GRF2 antibody (ABIN561125)

Nolz, Nacusi, Segovis, Medeiros, Mitchell, Shimizu, Billadeau: "The WAVE2 complex regulates T cell receptor signaling to integrins via Abl- and CrkL-C3G-mediated activation of Rap1." in: The Journal of cell biology, Vol. 182, Issue 6, pp. 1231-44, (2008) (PubMed).

Target Details for GRF2

Target: GRF2 (RAPGEF1) (Rap Guanine Nucleotide Exchange Factor (GEF) 1 (RAPGEF1))

Alternative Name: RAPGEF1

Background: Full Gene Name: Rap guanine nucleotide exchange factor (GEF) 1
Synonyms: C3G,DKFZp781P1719,GRF2

Gene ID: 2889

Pathways: Interferon-gamma Pathway, Neurotrophin Signaling Pathway, Platelet-derived growth Factor Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor