CHRNA4 antibody (AA 29-242)

Catalog No. ABIN5611309

The Mouse Monoclonal anti-CHRNA4 antibody (Clone 7B4H1) (ABIN5611309) specifically detects CHRNA4 in ELISA. The antibody is reactive with Human samples.

Quick Overview for CHRNA4 antibody (AA 29-242) (ABIN5611309)

Target: CHRNA4 (Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CHRNA4 antibody is un-conjugated

Application: ELISA

Clone: 7B4H1

Product Details anti-CHRNA4 Antibody

Binding Specificity: AA 29-242

Purpose: CHRNA4 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CHRNA4 (AA: 29-242) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for CHRNA4

Target: CHRNA4 (Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4))

Alternative Name: CHRNA4

Background: This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Alternative splicing results in multiple transcript variants.

Molecular Weight: 70 kDa

Gene ID: 1137

UniProt: P43681

Pathways: Synaptic Membrane