CD207 antibody (AA 155-328)

Catalog No. ABIN5611331

This Mouse Monoclonal antibody specifically detects CD207 in ELISA and FACS. It exhibits reactivity toward Human.

Quick Overview for CD207 antibody (AA 155-328) (ABIN5611331)

Target: CD207 (CD207 Molecule, Langerin (CD207))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD207 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Clone: 1C5A1

Product Details anti-CD207 Antibody

Binding Specificity: AA 155-328

Purpose: CD207 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD207 (AA: 155-328) expressed in E. Coli.

Isotype: IgG2b

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for CD207

Target: CD207 (CD207 Molecule, Langerin (CD207))

Alternative Name: CD207

Background: The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity.

Molecular Weight: 36.7 kDa

UniProt: Q9UJ71