GLRA1 antibody (AA 29-154)

Catalog No. ABIN5611339

Product Details anti-GLRA1 Antibody

Target: GLRA1 (Glycine Receptor, alpha 1 (GLRA1))

Binding Specificity: AA 29-154

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GLRA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS), Neutralization (Neut)

Purification: purified

Immunogen: Purified recombinant fragment of human GLRA1 (AA: extra 29-154) expressed in E. coli.

Clone: 7F8E2

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: N/A, IHC: N/A

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

Target Details for GLRA1

Target: GLRA1 (Glycine Receptor, alpha 1 (GLRA1))

Alternative Name: GLRA1 (GLRA1 Products)

Synonyms: GLYRA1 antibody, HKPX1 antibody, STHE antibody, [a]Z1 antibody, B230397M16Rik antibody, nmf11 antibody, oscillator antibody, ot antibody, spasmodic antibody, spd antibody, glycine receptor alpha 1 antibody, glycine receptor, alpha 1 antibody, glycine receptor, alpha 1 subunit antibody, GLRA1 antibody, Glra1 antibody, glra1 antibody

Background:

Description: The protein encoded by this gene is a subunit of a pentameric inhibitory glycine receptor, which mediates postsynaptic inhibition in the central nervous system. Defects in this gene are a cause of startle disease (STHE), also known as hereditary hyperekplexia or congenital stiff-person syndrome. Multiple transcript variants encoding different isoforms have been found.

Aliases: STHE, HKPX1

Molecular Weight: 52.6 kDa

Gene ID: 2741

HGNC: 2741

Pathways: Synaptic Membrane