IDH2 antibody (AA 354-451)

Catalog No. ABIN561418

This Mouse Monoclonal antibody specifically detects IDH2 in WB, ELISA and IHC (p). It exhibits reactivity toward Human.It has been mentioned in 1 publication

Quick Overview for IDH2 antibody (AA 354-451) (ABIN561418)

Target: IDH2 (Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IDH2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 5F11

Product Details anti-IDH2 Antibody

Binding Specificity: AA 354-451

Purpose: Mouse monoclonal antibody raised against a partial recombinant IDH2.

Sequence: HYREHQKGRP TSTNPIASIF AWTRGLEHRG KLDGNQDLIR FAQMLEKVCV ETVESGAMTK DLAGCIHGLS NVKLNEHFLN TTDFLDTIKS NLDRALGR

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: IDH2 (NP_002159, 354 a.a. ~ 451 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-IDH2 antibody (ABIN561418)

Gambichler, Terras, Kreuter, Skrygan: "Altered global methylation and hydroxymethylation status in vulvar lichen sclerosus: further support for epigenetic mechanisms." in: The British journal of dermatology, Vol. 170, Issue 3, pp. 687-93, (2014) (PubMed).

Target Details for IDH2

Target: IDH2 (Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))

Alternative Name: IDH2

Background: Full Gene Name: isocitrate dehydrogenase 2 (NADP+), mitochondrial
Synonyms: ICD-M,IDH,IDHM,IDP,IDPM,mNADP-IDH

Gene ID: 3418

NCBI Accession: NM_002168

Pathways: Warburg Effect