K-RAS antibody (AA 1-188)
-
- Target See all K-RAS (KRAS) Antibodies
- K-RAS (KRAS) (GTPase Kras (KRAS))
-
Binding Specificity
- AA 1-188
-
Reactivity
- Human
-
Host
- Mouse
-
Clonality
- Monoclonal
-
Conjugate
- This K-RAS antibody is un-conjugated
-
Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- Purpose
- Mouse monoclonal antibody raised against a full length recombinant KRAS.
- Sequence
- MTEYKLVVVG AGGVGKSALT IQLIQNHFVD EYDPTIEDSY RKQVVIDGET CLLDILDTAG HEEYSAMRDQ YMRTGEGFLC VFAINNTKSF EDIHHYREQI KRVKDSEDVP MVLVGNKCDL PSRTVDTKQA QDLARSYGIP FIETSAKTRQ GVDDAFYTLV REIRKHKEKM SKDGKKKKKK SKTKCVIM
- Cross-Reactivity
- Human
- Characteristics
- Antibody Reactive Against Recombinant Protein.
- Immunogen
- KRAS (AAH13572, 1 a.a. ~ 188 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Clone
- 3B10-2F2
- Isotype
- IgG1
-
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Buffer
- In 1x PBS, pH 7.4
- Handling Advice
- Aliquot to avoid repeated freezing and thawing.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
-
-
Cell surface protease activation during RAS transformation: Critical role of the plasminogen receptor, S100A10." in: Oncotarget, Vol. 7, Issue 30, pp. 47720-47737, (2016) (PubMed).
: "Evidence for aldosterone-dependent growth of renal cell carcinoma." in: International journal of experimental pathology, Vol. 95, Issue 4, pp. 244-50, (2014) (PubMed).
: "Overexpression of DDX43 mediates MEK inhibitor resistance through RAS Upregulation in uveal melanoma cells." in: Molecular cancer therapeutics, Vol. 13, Issue 8, pp. 2073-80, (2014) (PubMed).
: "KRAS gene amplification in colorectal cancer and impact on response to EGFR-targeted therapy. ..." in: International journal of cancer. Journal international du cancer, Vol. 133, Issue 5, pp. 1259-65, (2013) (PubMed).
: "Analysis of k-ras nuclear expression in fibroblasts and mesangial cells." in: PLoS ONE, Vol. 5, Issue 1, pp. e8703, (2010) (PubMed).
: "
-
Cell surface protease activation during RAS transformation: Critical role of the plasminogen receptor, S100A10." in: Oncotarget, Vol. 7, Issue 30, pp. 47720-47737, (2016) (PubMed).
-
- Target
- K-RAS (KRAS) (GTPase Kras (KRAS))
- Alternative Name
- KRAS (KRAS Products)
- Target Type
- Viral Protein
- Background
-
Full Gene Name: v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
Synonyms: C-K-RAS,K-RAS2A,K-RAS2B,K-RAS4A,K-RAS4B,KI-RAS,KRAS1,KRAS2,NS3,RASK2 - Gene ID
- 3845
-