MIF antibody (AA 1-115)

Catalog No. ABIN561823

This Mouse Monoclonal antibody specifically detects MIF in WB, ELISA, IP and IHC (p). It exhibits reactivity toward Human. It has been mentioned in 2+ publications

Quick Overview for MIF antibody (AA 1-115) (ABIN561823)

Target: MIF (Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor) (MIF))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MIF antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 2A10-4D3

Product Details anti-MIF Antibody

Binding Specificity: AA 1-115

Purpose: Mouse monoclonal antibody raised against a full length recombinant MIF.

Sequence: MPMFIVNTNV PRASVPDGFL SELTQQLAQA TGKPPQYIAV HVVPDQLMAF GGSSEPCALC SLHSIGKIGG AQNRSYSKLL CGLLAERLRI SPDRVYINYY DMNAANVGWN NSTFA

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: MIF (AAH00447.1, 1 a.a. ~ 115 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-MIF antibody (ABIN561823)

Goh, Hong, Hong, Lee, Ju, Jeong, Cho, Kim, Lee: "eIF3m expression influences the regulation of tumorigenesis-related genes in human colon cancer." in: Oncogene, Vol. 30, Issue 4, pp. 398-409, (2011) (PubMed).

Hawkins, Verma, Lightfoot, Jain, Rawat, McNair, Caseltine, Mojsilovic, Gupta, Neethling, Almanza, Dooley, Hildebrand, Weidanz: "An HLA-presented fragment of macrophage migration inhibitory factor is a therapeutic target for invasive breast cancer." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 11, pp. 6607-16, (2011) (PubMed).

Target Details for MIF

Target: MIF (Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor) (MIF))

Alternative Name: MIF

Background: Full Gene Name: macrophage migration inhibitory factor (glycosylation-inhibiting factor)
Synonyms: GIF,GLIF,MMIF

Gene ID: 4282

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling