MTRR antibody (AA 1-110)

Catalog No. ABIN561873

Cited in 1 publication. The Mouse Monoclonal anti-MTRR antibody (Clone 1G7) (ABIN561873) specifically detects MTRR in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for MTRR antibody (AA 1-110) (ABIN561873)

Target: MTRR (5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase (MTRR))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MTRR antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 1G7

Product Details anti-MTRR Antibody

Binding Specificity: AA 1-110

Purpose: Mouse monoclonal antibody raised against a partial recombinant MTRR.

Sequence: MRRFLLLYAT QQGQAKAIAE EMCEQAVVHG FSADLHCISE SDKYDLKTET APLVVVVSTT GTGDPPDTAR KFVKEIQNQT LPVDFFAHLR YGLLGLGDSE YTYFCNGGKI

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: MTRR (NP_002445, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-MTRR antibody (ABIN561873)

Guise, Abbattista, Tipparaju, Lambie, Su, Li, Wilson, Dachs, Patterson: "Diflavin oxidoreductases activate the bioreductive prodrug PR-104A under hypoxia." in: Molecular pharmacology, Vol. 81, Issue 1, pp. 31-40, (2011) (PubMed).

Target Details for MTRR

Target: MTRR (5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase (MTRR))

Alternative Name: MTRR

Background: Full Gene Name: 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
Synonyms: MGC129643,MSR

Gene ID: 4552

NCBI Accession: NM_002454

Pathways: Methionine Biosynthetic Process