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CNOT3 antibody (AA 1-100)

CNOT3 Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 4B8 unconjugated
Catalog No. ABIN562024
  • Target See all CNOT3 Antibodies
    CNOT3 (CCR4-NOT Transcription Complex, Subunit 3 (CNOT3))
    Binding Specificity
    • 12
    • 8
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 1-100
    Reactivity
    • 39
    • 12
    • 11
    • 10
    • 8
    • 8
    • 8
    • 8
    • 5
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    Human
    Host
    • 37
    • 2
    Mouse
    Clonality
    • 37
    • 2
    Monoclonal
    Conjugate
    • 25
    • 4
    • 3
    • 3
    • 2
    • 2
    This CNOT3 antibody is un-conjugated
    Application
    • 33
    • 21
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    Purpose
    Mouse monoclonal antibody raised against a partial recombinant CNOT3.
    Sequence
    MADKRKLQGE IDRCLKKVSE GVEQFEDIWQ KLHNAANANQ KEKYEADLKK EIKKLQRLRD QIKTWVASNE IKDKRQLIDN RKLIETQMER FKVVERETKT
    Cross-Reactivity
    Human
    Characteristics
    Antibody Reactive Against Recombinant Protein.
    Immunogen
    CNOT3 (NP_055331, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Clone
    4B8
    Isotype
    IgG1
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    In 1x PBS, pH 7.4
    Handling Advice
    Aliquot to avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Inoue, Morita, Hijikata, Fukuda-Yuzawa, Adachi, Isono, Ikawa, Kawamoto, Koseki, Natsume, Fukao, Ohara, Yamamoto, Kurosaki: "CNOT3 contributes to early B cell development by controlling Igh rearrangement and p53 mRNA stability." in: The Journal of experimental medicine, Vol. 212, Issue 9, pp. 1465-79, (2015) (PubMed).

    Kamon, Katano, Hiraki-Kamon, Hishida, Nakachi, Mizuno, Okazaki, Suzuki, Hirasaki, Ueda, Nishimoto, Kato, Okuda: "Identification of Ccr4-not complex components as regulators of transition from partial to genuine induced pluripotent stem cells." in: Stem cells and development, Vol. 23, Issue 18, pp. 2170-9, (2014) (PubMed).

    Doidge, Mittal, Aslam, Winkler: "The anti-proliferative activity of BTG/TOB proteins is mediated via the Caf1a (CNOT7) and Caf1b (CNOT8) deadenylase subunits of the Ccr4-not complex." in: PLoS ONE, Vol. 7, Issue 12, pp. e51331, (2012) (PubMed).

    Aslam, Mittal, Koch, Andrau, Winkler: "The Ccr4-NOT deadenylase subunits CNOT7 and CNOT8 have overlapping roles and modulate cell proliferation." in: Molecular biology of the cell, Vol. 20, Issue 17, pp. 3840-50, (2009) (PubMed).

  • Target
    CNOT3 (CCR4-NOT Transcription Complex, Subunit 3 (CNOT3))
    Alternative Name
    CNOT3 (CNOT3 Products)
    Synonyms
    LENG2 antibody, NOT3 antibody, NOT3H antibody, A930039N10Rik antibody, cnot3 antibody, zgc:55934 antibody, wu:fi20g07 antibody, fb73b06 antibody, fc17h07 antibody, wu:fb73b06 antibody, wu:fc17h07 antibody, zgc:92813 antibody, CNOT3 antibody, Afu2g02070 antibody, AO090011000479 antibody, CG8426 antibody, Dmel\\CG8426 antibody, NOT3.5 antibody, NOT3/5 antibody, Not3 antibody, not3 antibody, not3/5 antibody, leng2 antibody, not3h antibody, CCR4-NOT transcription complex subunit 3 antibody, CCR4-NOT transcription complex, subunit 3 antibody, CCR4-NOT transcription complex, subunit 3b antibody, CCR4-NOT transcription complex, subunit 3a antibody, CCR4-NOT transcription complex subunit 3 S homeolog antibody, CNOT3 antibody, Cnot3 antibody, cnot3b antibody, cnot3a antibody, AFUA_2G02070 antibody, NFIA_034440 antibody, ACLA_092760 antibody, PMAA_089540 antibody, AFLA_043060 antibody, TSTA_125290 antibody, ANI_1_738064 antibody, AOR_1_812054 antibody, Not3 antibody, cnot3 antibody, cnot3.S antibody
    Background
    Full Gene Name: CCR4-NOT transcription complex, subunit 3
    Synonyms: KIAA0691,LENG2,NOT3,NOT3H
    Gene ID
    4849
    NCBI Accession
    NM_014516
    Pathways
    Stem Cell Maintenance
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